IMB-10
3-(o-Tolyl)-5-(3-phenyl-2-propenylidene)-2-thioxo-1,3-thiazolin-4-one Yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable thioxothiazolidine compound that displays anti-inflammatory properties. Shown to increase cell adhesion and lowers leukemia cell migration in vitro and leukocyte recruitment in vivo and displays anti-inflammatory properties. Binds to and stabilizes integrin aM I domain active conformation and enhances the ligands' (pro-MMP-9 and fibrinogen) binding ability. Purity: ≥98% by HPLC. Ref.: Bjorklund, M., et al. 2006. Biochemistry 45, 2862. | 
