Liquid. Sterile-filtered (0.22 µm) in 40 mM Tris-HCl, pH 7.4, carrier-free. AVOID FREEZE/THAW CYCLES. Recombinant, human g-interferon expressed in E. coli. A multi-functional protein consisting of 144 amino acids. Exhibits antiviral and antitumor properties. Regulates the development of specific immune responses. Biological activity: ED₅₀ = 0.5-3.0 ng/ml as measured by inhibition (cytostasis) of human WiDr cells.. Note: 1 MU = 1,000,000 units.

Merck Index: 14, 4992
Ref.: Kohji, K., et al. 1994. J. Int. J. Cancer 58, 380. Kolb, J.P., et al. 1994. J. Biol. Chem. 269, 9811. Müller, U., et al. 1994. Science 264, 1918. Zahedi, K., et al. 1994. J. Biol. Chem. 269, 9669. Shuai, K., et al. 1993. Science 261, 1744. Wilson, K.C., and Finbloom, D.S. 1992. Proc. Natl. Acad. Sci. USA 89, 11964. Meager, A. 1987. Lymphokines and Interferons, A Practical Approach (Clemens, M.J., et al., eds.) p. 129, IRL Press, Oxford.