Return to our Home Page


Tech Resources
Data Sheet
Technical Bulletin
MSDS - English
Other Languages
Selected Citations
Certificate of Analysis
Store
2 to 8°C2 to 8°C
Ship
Shipped at Ambient TemperatureAmbient
HarmfulHarmful
Note: Store and Ship conditions may differ.
See Key
PubChem
SID: 26758971
Also available in:
bulkRequest a Quote!
  Ionomycin, Free Acid, Streptomyces conglobatus
Cat. No. 407950  
All Categories » Calbiochem » Biochemicals » Ionophores

Light yellow film. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. Highly specific for divalent cations and more effective than A23187 (Cat. No. 100105) as a mobile ion carrier for Ca2+. Complexes with Ca2+ between pH 7 and 9.5. In contrast to A23187, it is not fluorescent. Useful for studies of Ca2+ transport across biological membranes and measurement of cytoplasmic free Ca2+. Induces apoptotic neuronal degeneration in embryonic cortical neurons and cell cycle arrest in the G1 phase in mature Burkitt lymphoma cell lines. Purity: ≥90% by HPLC. Absorption max. (280 nm, MeOH): 18,600 M-1cm-1. RTECS NO0600000, CAS 56092-81-0.

Ref.: Aagaard-Tillery, K.M., and Jelinek, D.F. 1995. J. Immunol. 155, 3297. Takei, N., and Endo, Y. 1994. Brain Res. 652, 65. Dupuy d’Angeac, A., et al. 1993. J. Cell Physiol. 154, 44. Lee, H.C. 1993. J. Biol. Chem. 268, 293. Kuznetsov, G., et al. 1992. J. Biol. Chem. 267, 3932. Toeplitz, B.K., et al. 1979. J. Am. Chem. Soc. 101, 3344. Liu, C.M., and Hermann, T.E. 1978. J. Biol. Chem. 253, 5892.
R: 22; S: 36

Need additional information about this product? Email our Technical Service department at: technical@calbiochem.com

 Related information for this product is available:

EMD Chemicals Inc. USD list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.

Size
In Stock
Qty
Select Country Above
For Pricing Information
1 mgY$104.00
5 mgY$373.00
10 mgY$657.00


SolubilityMolecular FormulaMol. Wt.
DMSO or MeOH C41H72O9 709.0 


Alternate Products:
407950: Ionomycin, Free Acid, Streptomyces conglobatus
407952: Ionomycin, Calcium Salt, Streptomyces conglobatus

Related Products:
100105: A23187, Free Acid, Streptomyces chartreusensis
205535: CA 1001
407950: Ionomycin, Free Acid, Streptomyces conglobatus
676377: Valinomycin, Streptomyces fulvissimus

Related Literature:

Calcium Metabolism and Related Products Brochure

Caspases and other Apoptosis Related Tools Brochure

Tools and Tips for Analyzing Apoptosis

Material Safety Data Sheets:
407950: Ionomycin, Free Acid, Streptomyces conglobatus - English
Bulgarian
Danish
Dutch
Finnish
French
German
Greek
Hungarian
Italian
Korean
Norwegian
Polish
Portuguese
Spanish
Swedish

Related Categories:
All Categories » Calbiochem » Biochemicals » Ionophores

Selected Citations:
  1. Jonathan Rios-Doria, et al. (2004) Cleavage of b-catenin by calpain in prostate and mammary tumor cells. Cancer Research 64, 7237-7240.