(2-Naphthylvinyl Ketone)
ZM 449829 White waxy solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. PACKAGED UNDER INERT GAS. A breakdown product of JAK3 Inhibitor-IV (Cat. No. 420121) with similar inhibitory potency (pIC50 = 6.8 for JAK3; 5.0 for EGF-R; 4.7 for JAK1). Also inhibits STAT-5 phosphorylation and T-cell proliferation. Purity: ≥98% by HPLC. CAS 4452-06-6. Ref.: Brown, G.R., et al. 2000. Bioorg. Med. Chem. Lett. 10, 575.
Sold under license of PCT Application W098/22,103. | 
