N1-Methyl-1,9-pyrazoloanthrone Yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A useful negative control for JNK Inhibitor II (SP600125, Cat. No. 420119). Inhibits JNK2 and JNK3 only at much higher concentrations (IC50 = 18 µM and 24 µM, respectively) compared to SP600125 (IC50 = 40 nM and 90 nM, respectively). Purity: ≥97% by HPLC. Ref.: Shin, M., and Boyd, Y.D. 2002. Biochim. Biophys. Acta 1589, 311. Bennett, B.L., et al. 2001. Proc. Natl. Acad. Sci. USA 98, 13681. |
