H2N-RPKRPTTLNLF-NH2
Truncated Inhibitor based on JNK-Interacting Protein 1 Lyophilized. Supplied as a trifluoroacetate salt. PROTECT FROM LIGHT. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A murine JIP-1 JNK-binding domain- (JBD) derived 11-mer peptide that directly interacts with JNK (KD in low µM range) and specifically inhibits JNK kinase activity without inhibitory effects towards ERK or p38. The inhibition is not limited only to JBD-containing substrates and is found to be mixed/non-competitive with respect to ATP. JNK Inhibitor VII, TAT-TI-JIP153-163, Cell-Permeable, is also available (Cat. No. 420134). Purity: ≥97% by HPLC. H-Arg-Pro-Lys-Arg-Pro-Thr-Thr-Leu-Asn-Leu-Phe-NH2 Ref.: Barr, R.K., et al. 2004. J. Biol. Chem. 279, 36327. Barr, R.K., et al. 2002. J. Biol. Chem. 277, 10987. | 
