cis-1-Acetyl-4-[4-[[2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]piperazine
R-41400 Off-white solid. An inhibitor of cytochrome P-450 in steroid biosynthesis. An antifungal agent that displays potent anti-metastatic, anti-neoplastic, and anti-psoriatic activities. Also acts as an inhibitor of 5-lipoxygenase (5-LO; IC50 = 26 µM) and thromboxane synthase activities. Purity: ≥98% by HPLC. RTECS TK7912300, CAS 65277-42-1. Merck Index: 14, 5302
Ref.: van Wauwe, J.P., and Janssen, P.A.J. 1989. J. Med. Chem. 32, 2231. Beetens, J.R., et al. 1986. Biochem. Pharmacol. 35, 883. Lambert, A., et al. 1986. Biochem. Pharmacol. 35, 3999. Tucker, W.F.G., and MacNeil, S. 1986. Br. Med. J. 293, 882. Lelcuk, S., et al. 1984. J. Trauma 24, 393.
R: 25-40-63-36/37/38; S: 22-26-36 |
