Yellow solid. A structurally unique marine toxin. Inhibits actin polymerization in vitro and disrupts microfilament organization as well as microfilament-mediated processes; 10 to 100-fold more potent than cytochalasins. Purity: ≥98% by TLC. CAS 76343-94-7. Merck Index: 14, 5378 Ref.: Spector, I., et al. 1989. Cell Motil. Cytoskeleton 13, 127. de Oliveira, C.A., and Mantovani, B. 1988. Life Sci. 43, 1825. Coue, M., et al. 1987. FEBS Lett. 213, 316. Spector, I., et al. 1983. Science 219, 493. R: 20/21/22; S: 36 |