5(S)-Hydroxy-6(R)-S-glutathionyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid LTC4 Liquid. In MeOH:NH4OAc buffer (65:35), pH 5.6. Implicated in renal vasoconstriction associated with sepsis. Also plays a role in bronchioconstriction. Produced by conjugation of LTA4 with reduced glutathione. Reported to be a tight binding inhibitor of microsomal glutathione transferase-1. Has been implicated in pathophysiology of asthma. Purity: ≥98% by HPLC. RTECS MB9143500, CAS 72025-60-6. Merck Index: 14, 5455 Ref.: Bannenberg, G., et al. 1999. J. Biol. Chem. 274, 1994. Shimizu, T., et al. 1994. Pediatr. Pulmonol. 18, 129. R: 11-23/24/25-39/23/24/25; S: 16-7-36/37-45 |