5(S)-Hydroxy-6(R)-S-cysteinylglycinyl-7-trans-9-trans-11-cis-14-cis-eicosatetraenoic Acid LTD4 Liquid. 50 µg/ml in MeOH:NH4OAc buffer (70:30), pH 5.6. Implicated in renal and bronchial vasoconstriction. Significant mediator in asthmatic reactions. Reported to increase intracellular Ca2+ and activate MAP kinase in monospecific leukemic THP-1 cells. Purity: >98% by HPLC. RTECS MB9143000, CAS 73836-78-9. Merck Index: 14, 5455 Ref.: Hoshino, M., et al. 1998. J. Biol. Chem. 273, 4878. Iwamoto, I., et al. 1995. Int. Arch. Allergy Immunol. 108, 68. Jedlitschky, G., et al. 1991. J. Biol. Chem. 266, 24763. R: 11-23/24/25-39/23/24/25; S: 7-16-36/37-45 |