LXA4
5(S),6(R),15(S)-Trihydroxyeicosa-7-trans-9-trans-11-cis-13-trans-tetraenoic Acid Liquid. In Ethanol. Potent inhibitor of cytotoxic activity of human natural killer cells; shown to be as potent as LTB4 in stimulating human neutrophils to generate superoxides. Involved in contractile responses and acts as a potent activator of human protein kinase C. Stimulates rapid lipid remodeling and pertussis-sensitive release of arachidonic acid in polymorphonuclear leukocytes. Stimulates MAP kinases via activation of G protein-coupled receptors. Purity: ≥95% by HPLC. Caution! Product contains volatile liquid. Keep product cold at all times. CAS 89663-86-5. Ref.: McMahon, B., et al. 2000. J. Biol. Chem. 275, 27566. Soyombo, O., et al. 1994. Allergy 49, 230. Flore, S., et al. 1992. J. Biol. Chem. 267, 16168. Badr, K.F., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 3438.
R: 11-36/37/38; S: 16-26-36-7 |
