White solid. Selective, orally active leukotriene D4 antagonist (Ki = 630 nM for 3H-LTD4 binding to guinea pig lung membranes). Activates peroxisome proliferation-activated receptors (PPARs). Purity: ≥98% by TLC. RTECS KM5780800, CAS 88107-10-2. Ref.: Cannon, J.R., and Eacho, P.I. 1991. Biochem. J. 280, 387. Aharony, D., et al. 1987. J. Pharmacol. Exp. Ther. 243, 921. Fleisch, J.H., et al. 1985. J. Pharmacol. Exp. Ther. 233, 148.
R: 22; S: 36 |
