Ac-Pro-Leu-Gly-(2-mercapto-4-methylpentanoyl)-Leu-Gly-OEt
Gelatinase A/Gelatinase B Substrate II White solid. PROTECT FROM LIGHT. An exceptional thiopeptide that is used as a substrate for the rapid, sensitive, and continuous spectrophotometric assay of Type IV collagenases, MMP-2 (gelatinase A), and MMP-9 (gelatinase B). Also acts as a substrate for vertebrate collagenase. Cleavage is monitored at 324 nm. Purity: ≥97% by HPLC. Ac-Pro-Leu-Gly-SCH[CH2CH(CH3)2]-CO-Leu-Gly-OC2H5 Ref.: Weingarten, H., et al. 1985. Anal. Biochem. 147, 437. Weingarten, H., et al. 1985. Biochemistry 24, 6730. |
