N-Hydroxy-1,3-di-(4-methoxybenzenesulphonyl)-5,5-dimethyl-[1,3]-piperazine-2-carboxamide Off-white solid. PACKAGED UNDER INERT GAS. A potent, reversible, broad-range inhibitor of matrix metalloproteinases. Inhibits MMP-1 (IC50 = 24 nM), MMP-3 (IC50 = 18.4 nM), MMP-7 (IC50 = 30 nM), and MMP-9 (IC50 = 2.7 nM). Purity: ≥95% by HPLC. CAS 203915-59-7. Ref.: Pikul, S., et al. 1998. J. Med. Chem. 41, 3568. |
