N-Hydroxy-1-(4-methoxyphenyl)sulfonyl-4-(4-biphenylcarbonyl)piperazine-2-carboxamide White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A piperazine-based, cell-permeable, and highly potent inhibitor of MMP-9 (IC50 = 900 pM) and MMP-13 (IC50 = 900 pM). Inhibits MMP-1 and MMP-3 at much higher concentrations (IC50 = 43 nM and 23 nM, respectively). Also acts as an inhibitor of MMP-7 (IC50 = 930 nM). Purity: ≥95% by HPLC. Ref.: Cheng, M., et al. 2000. J. Med. Chem. 43, 369. | 
