MCA-PLA-C(OMeBz)-WAR(Dpa)-NH₂
MT1-MMP Substrate I, Fluorogenic

White lyophilized solid. Supplied as a trifluoroacetate salt. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A specific fluorescence resonance energy transfer (FRET) peptide substrate for the detection of MMP activity. (k_cat/K_m = 7.3 x 10⁵ M^-1s^-1 for MMP-14 (MT1-MMP) and 3.6 x 10⁴ M^-1s^-1 for MMP-11 at 25°C, pH 7.5). Purity: ≥97% by HPLC. Excitation max.: ~328 nm, Emission max.: ~400 nm

MCA-Pro-Leu-Ala-Cys(p-OMeBz)-Trp-Ala-Arg(Dpa)-NH₂ Dpa = N³-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl, Bz = Benzyl

Ref.: Mucha, A., et al. 1998. J. Biol. Chem. 273, 2763.