4-Dibenzofuran-2′-yl-4-hydroximino-butyric Acid White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent and competitive inhibitor of both human and rabbit MMP-3 catalytic domains (wild type and mutants) with Ki values in the low µM range. The functional groups, namely the oxime and the carboxyl, are shown to interact with the active site zinc. Purity: >95% by HPLC. Ref.: Johnson, L.L., et al. 1999. J. Biol. Chem. 274, 24881. |