4-(4′-Biphenyl)-4-hydroxyimino-butyric Acid White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A potent and competitive inhibitor of MMP-3. Inhibits both human and rabbit MMP-3 (wild type and mutants) with Ki values in the low µM range. The functional groups, namely the oxime and the carboxyl, are shown to interact with the active site zinc. Purity: ≥95% by HPLC. Ref.: Johnson, L.L., et al. 1999. J. Biol. Chem. 274, 24881. | 
