(4-(4-(Methanesulfonamido)phenoxy)phenylsulfonyl)methyloxirane White solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. PACKAGED UNDER INERT GAS. An oxirane analog of SB-3CT, pMS (Cat. No. 444285) that acts as a selective, active site-binding, irreversible inhibitor of MMP-2 (Ki = 2.4 µM). Although less potent, it exhibits enhanced selectivity towards MMP-2 (Ki = 45 and 379 µM for MMP-1 and MMP-7, respectively) than SB-3CT, pMS. Purity: ≥97% by HPLC. Ref.: Ikejiri, M., et al. 2005. J. Biol. Chem. 280, 33992. |
