KiSS-1 (112-121)
Kisspeptin-10
H-YNWNSFGLRF-NH2 White lyophilized solid. Supplied as a trifluoroacetate salt. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A decapeptide with C-terminally amidated LRF-motif that acts as a potent and selective agonist of AXOR12 and hOT7T175 (a novel human G-protein-coupled receptors). Induces an increase in intracellular Ca2+ levels in CHO/h175 and CHO/AXOR12:Gqi5 cells and exhibits about 8-fold higher receptor binding affinity (Ki = 42 pM) compared to Metastin (Cat. No. 445885). Purity: ≥97% by HPLC. H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 Ref.: Kotani, M., et al. 2001. J. Biol. Chem. 276, 34631. Ohtaki, T., et al. 2001. Nature 411, 613. Muir, A.I., et al. 2001. J. Biol. Chem. 276, 28969. | 
