(1S,2R)-D-erythro-2-(N-Myristoylamino)-1-phenyl-1-propanol Solid. A synthetic analog of ceramide. Shown to selectively inhibit alkaline ceramidase both in vitro and in HL-60 cells (IC50 = 1-5 µM for alkaline ceramidase versus IC50 > 500 µM for acid ceramidase). This inhibition results in over 3-fold increase in endogenous ceramide in treated cells due to lack of breakdown of ceramide to sphingosine. Purity: ≥98% by NMR. CAS 143492-38-0. Ref.: Bielawska, A., et al. 1996. J. Biol. Chem. 271, 12646. Hannun, Y.A. 1996. Science 274, 1855. | 
