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  4-{[3′,4′-(Methylenedioxy)benzyl]amino}-6-methoxyquinazoline
Cat. No. 475250  
All Categories » Calbiochem » Inhibitors » Phosphodiesterase Inhibitors

White solid. Potent and specific inhibitor of cGMP-specific phosphodiesterase (PDE V; IC50 = 230 nM). Elevates the intracellular cGMP level without causing any change in the cAMP level in isolated porcine coronary arteries. Has no effect on other PDE isozymes. Purity: ≥98% by TLC.

Ref.: Takase, Y., et al. 1994. J. Med. Chem. 37, 2106.

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1 mgYN/A

SolubilityMolecular FormulaMol. Wt.
DMSO C17H15N3O3 309.3 


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475250: 4-{[3′,4′-(Methylenedioxy)benzyl]amino}-6-methoxyquinazoline - English
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All Categories » Calbiochem » Inhibitors » Phosphodiesterase Inhibitors