MCYST-RR Off-white solid. Arg-Arg analog of Microcystin-LR (Cat. No. 475815) that is less toxic. Inhibits protein phosphatase 2A (IC50 = 3.4 nM). Useful for comparative structure and function studies. Purity: ≥95% by HPLC. CAS 111755-37-4. Ref.: Shirai, M., et al. 1991. Appl. Environ. Microbiol. 57, 1241. Mastsushima, R., et al. 1990. Biochem. Biophys. Res. Commun. 171, 867. Meriluoto, J.A., et al. 1990. J. Chromatography 509, 309. Carmichael, W.W. 1989. in Natural Toxins (Ownby, C.L., and O’Dell, G.V., Eds.) p. 3, Pergamon, Elmsford, New York.
R: 26/27/28-36/37/38-43; S: 26-36/37/39-45
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