b-[N-(3-Hydroxy-4-pyridone)]-a-aminopropionic Acid
Leucenol

Off-white solid. A naturally-occurring rare amino acid derivative isolated from Leucaena seeds. An extremely effective inhibitor of DNA replication in mammalian cells that may act by preventing the formation of replication forks. Inhibits the activity of mitochondrial and cytosolic serine hydroxymethyltransferases. Purity: ≥98% by TLC. RTECS UT7610000, CAS 500-44-7.

Merck Index: 14, 6199
Ref.: Lin, H.-B., et al. 1996. J. Biol. Chem. 271, 2548. Ebien, S.T., et al. 1995. Cancer Res. 55, 1994. Urbani, L., et al. 1995. Exp. Cell Res. 219, 159. Wang, Y., et al. 1995. Exp. Cell Res. 217, 84.
R: 20/21/22; S: 22-36