CMPD1
4-(2′-Fluorobiphenyl-4-yl)-N-(4-hydroxyphenyl)-butyramide
MAPKAPK2a Inhibitor
Mitogen-activated protein kinase-activated protein kinase 2a Inhibitor Pale yellow solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A p-amidophenolic compound that selectively inhibits the phosphorylation of MK2a (mitogen-activated protein kinase-activated protein kinase 2a; Kiapp = 330 nM) by p38a in a non-ATP-competitive manner. Does not block the kinase activity of p38a towards the other two known p38 substrates, MBP and ATF-2. Purity: ≥95% by HPLC. CAS 41179-33-3. Ref.: Davidson, W., et al. 2004. Biochemistry 43, 11658. Lukas, S.M., et al. 2004. Biochemistry 43, 9950. | 
