Mn(III)tetrakis(4-benzoic acid)porphyrin Chloride Brown solid. PROTECT FROM LIGHT. PROTECT FROM MOISTURE. Cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. Protects endothelial cells in a dose-dependent manner (EC50 ~40 µM) against paraquat (2 mM). Inhibits the oxidation of Dihydrorhodamine 123 (Cat. No. 309825) by peroxynitrite, but does not scavenge nitric oxide (NO). Purity: ≥95% by TLC. Ref.: Aladag, M. A., et al. 2003. Acta Neurochir. 145, 673. Szabo, C., et al. 1996. FEBS Lett. 381, 82. Day, B.J., et al. 1995. J. Pharmacol. Exp. Ther. 275, 1227. Faulkner, K.M., et al. 1994. J. Biol. Chem. 269, 23471. |
