(E)-3-[[[3-[2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-[[3-dimethylamino)-3-oxopropyl]thio]methyl]thio]-propanoic Acid, Sodium Salt L 660711, Sodium Salt Off-white solid. PROTECT FROM MOISTURE. HYGROSCOPIC. A selective, competitive antagonist of leukotriene D4 (LTD4) (Ki = 2.1 nM for inhibition of [3H]LTD4 binding to human lung membranes). Also inhibits multidrug resistance-associated protein 1 (MRP1). Purity: ≥90% by HPLC. CAS 115104-28-4. Ref.: Olson, D.P., et al. 2001. Cytometry 46, 105. Van der Kolk, D.M., et al. 1998. Clin. Cancer Res. 4, 1727. Jones, T.R., et al. 1989. Can. J. Physiol. Pharmacol. 67, 17. |