1-(5-Iodonaphthalene-1-sulfonyl)homopiperazine, HCl White solid. PROTECT FROM LIGHT. HYGROSCOPIC. A cell-permeable, potent, and selective inhibitor of myosin light chain kinase (Ki = 300 nM). Inhibits protein kinase A (Ki = 21 µM) and protein kinase C (Ki = 42 µM) at much higher concentrations. Purity: >98% by TLC. CAS 110448-33-4. Ref.: Krarup, T., et al. 1998. Am. J. Physiol. 275, C239. Saitoh, M., et al. 1987. J. Biol. Chem. 262, 7796. |
