1-(5-Chloronaphthalene-1-sulfonyl)homopiperazine, HCl White solid. PROTECT FROM LIGHT. HYGROSCOPIC. Cell-permeable inhibitor of myosin light chain kinase (Ki = 3.8 µM), protein kinase A (Ki = 32 µM), and protein kinase C (Ki = 54 µM). Also inhibits catecholamine secretion in intact and permeabilized chromaffin cells. Purity: ≥99% by TLC. CAS 105637-50-1. Ref.: Reig, J.A., et al. 1993. Neurochem. Res. 18, 317. Nagatsu, T., et al. 1987. Biochem. Biophys. Res. Commun. 143, 1045. Saitoh, M., et al. 1987. J. Biol. Chem. 262, 7796. Saitoh, M., et al. 1986. Biochem. Biophys. Res. Commun. 140, 280. |
