Dimethylbenzylammonium Propane Sulfonate White solid. HYGROSCOPIC. A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Easily removed by dialysis. At 1 M, NDSB-256 will restore 30% of the enzymatic activity of denatured egg white lysozyme; at 800 mM it will restore 16% of the enzymatic activity of denatured b-galactosidase. Purity: ≥99% by TLC. CAS 81239-45-4. Ref.: Goldberg, M.E., et al. 1996. Folding & Design 1, 21. R: 36/37/38; S: 26-36 |