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SID: 26759236

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Inhibitor Database
  NF-kB Activation Inhibitor II, JSH-23
Cat. No. 481408  
All Categories » Calbiochem » Inhibitors » NF-kB Activation

4-Methyl-N1-(3-phenylpropyl)benzene-1,2-diamine

Off-white solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable diamino compound that selectively blocks nuclear translocation of NF-kB p65 and its transcription activity (IC50 = 7.1 µM in a NF-kB reporter assay using RAW 264.7) without affecting IkB degradation. Shown to suppress DNA-binding of NF-kB and downregulate LPS-induced gene expression and apoptotic chromatin condensation. Purity: ≥95% by HPLC.

Ref.: Shin, H.M., et al. 2004. FEBS Lett. 571, 50.

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5 mgYN/A

SolubilityMolecular FormulaMol. Wt.
DMSO C16H20N2 240.3 


Related Literature:

Biologics 32.1

Biologics 32.3

Material Safety Data Sheets:
481408: NF-kB Activation Inhibitor II, JSH-23 - English
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Related Categories:
All Categories » Calbiochem » Inhibitors » NF-kB Activation