Yellow solid. PROTECT FROM LIGHT. Relatively selective blocker of L-type Ca²⁺ channels. One of the most extensively studied blockers of 1,4-dihydropyridine-type Ca²⁺ channels, and a pharmacologically-useful vasodilator. Induces apoptosis in human glioblastoma cells. Purity: ≥98% by UV. RTECS US7975000, CAS 21829-25-4.

Merck Index: 14, 6528
Ref.: Reid, K., et al. 1997. J. Pharmacol. Exp. Ther. 283, 993. Kondo, S., et al. 1995. J. Neurosurg. 82, 469. Antkiewicz-Michaluk, L., et al. 1994. Eur. J. Pharmacol. 254, 9. Calabresi, P., et al. 1994. J. Neurosci. 14, 4871. Akman, M.S., et al. 1993. Endocrinology 132, 1286. Cirillo, M., et al. 1993. Circ. Res. 72, 847. Young, R.J., et al. 1993. Biochim. Biophys. Acta 1146, 81. Janis, R., et al. 1987. Adv. Drug Res. 16, 311.
R: 22; S: 36-26