NPPB Yellow solid. Potent Cl– channel blocker (IC50 = 100 nM-100 µM), depending on channel subtype and assay method. Inhibits cyclooxygenase (IC50 = 8 µM). Purity: ≥98% by TLC. CAS 107254-86-4. Ref.: Illek, B., et al. 1992. Am. J. Physiol. 263, C644. Kirk, K., et al. 1992. J. Biol. Chem. 267, 23475. Breuer, W., et al. 1989. Biochem. Biophys. Res. Commun. 163, 398. Wangermann, P., et al. 1986. Pflugers Arch. 407, S128. |