Calbiochem: 487910: (?)-S-Nitroso-N-acetylpenicillamine

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	SID: 26759266

��	(�)-S-Nitroso-N-acetylpenicillamine

Cat. No. 487910��

All Categories � Calbiochem � Biochemicals � Nitric Oxide and Oxidative Stress � Nitric Oxide Donors/Precursors

SNAP

Pale green solid. PROTECT FROM LIGHT. Nitric oxide donor that mimics the actions of nitric oxide, including relaxation of isolated bovine coronary artery rings (EC₅₀ = 130 nM). Markedly activates soluble guanylate cyclase. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 5 mg. Purity: ≥95% by HPLC. CAS 79032-48-7.

Ref.: Nishio, E., et al. 1996. Biochem. Biophys. Res. Commun. 221, 163. Askew, S.C., et al. 1995. Bioorg. Med. Chem. 3, 1. Fehsel, K., et al. 1995. J. Immunol. 155, 2858. Gopalkrishna, R., et al. 1993. J. Biol. Chem. 268, 27180. Southan, E., and Garthwaite, J. 1991. Neurosci. Lett. 130, 107. Henry, P.J., et al. 1989. J. Pharmacol. Exp. Ther. 248, 762.
R: 36/37/38; S: 26-36

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1 set Y N/A
20 mg Y N/A

Solubility Molecular Formula Mol. Wt.
DMSO, EtOH, or MeOH� C₇H₁₂N₂O₄S� 220.2�

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487910: (�)-S-Nitroso-N-acetylpenicillamine - English
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Related Categories:
All Categories � Calbiochem � Biochemicals � Nitric Oxide and Oxidative Stress � Nitric Oxide Donors/Precursors

Selected Citations:
Bysani Chandrasekar, et al. (2005) The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Akt, c-J. Journal of Biological Chemistry 280, 26263-26277.

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