Calbiochem: 487928: Nocodazole

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��	Nocodazole

Cat. No. 487928��

All Categories � Calbiochem � Biochemicals � Extracellular Matrix, Adhesion and Cytoskeletal Research Tools

Methyl-[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamate
R17934

Pale yellow solid. Inhibitor of mitosis. Has highly specific antimicrotubular activity for mammalian cells in culture. Promotes tubulin depolymerization. Purity: ≥98% by HPLC. RTECS DD6521000, CAS 31430-18-9.

Ref.: Bunz, F., et al. 1998. Science 282, 1497. Fleischman, L.F., et al. 1993. Oncogene 8, 771. Pomies, P., and Block, M.R. 1992. Biochem. Biophys. Res. Commun. 189, 1429. Rennison, M.E., et al. 1992. J. Cell Sci. 102, 239. Thyberg, J., and Moskalewski, S. 1992. J. Cell Sci. 103, 1167.
R: 40-63; S: 36

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10 mg Y N/A

Solubility Molecular Formula Mol. Wt.
DMSO� C₁₄H₁₁N₃O₃S� 301.3�

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Selected Citations:
Meng Qiao, et al. (2006) Cell cycle-dependent phosphorylation of the RUNX2 transcription factor by cdc2 regulates endothelial cell proliferation. Journal of Biological Chemistry 281, 7118-7128.

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