H-FNAPFDVGIKLSGVQYQQHSQAL-NH2 White lyophilized solid. Supplied as a trifluoroacetate salt PROTECT FROM LIGHT. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A proghrelin-derived 23 amino acid peptide that exhibits the exact opposite effect as ghrelin and acts as an anorexic hormone. Shown to activate the orphan G protein-coupled receptor GPR39 (Kd = 1 nM) and stimulate cAMP production in GPR39-expressing CHO and GPR39-expressing HEK293T cells. Suppresses cumulative food intake, inhibits jejunal contraction, and decreases weight gain in mice in vivo. Purity: ≥97% by HPLC. H2N-Phe-Asn-Ala-Pro-Phe-Asp-Val-Gly-Ile-Lys-Leu-Ser-Gly-Val-Gln-Tyr-Gln-Gln-His-Ser-Gln-Ala-Leu-NH2 Ref.: Zhang, J.V., et al. 2005. Science 310, 996. | 
