N-2-Hydroxyethyl-9(Z)-octadecenamide White solid. A potent inhibitor of the ceramidase found in human kidney and cerebellum. Blocks the conversion of ceramide to sphingosine. A specific inhibitor of acid ceramidase (IC50 ~ 500 µM). Purity: ≥98% by TLC. CAS 111-58-0. Ref.: Pahan, K., et al. 1998. J. Biol. Chem. 273, 2591. Ping, S.E., and Barrett, G.L. 1998. J. Neurosci. Res. 54, 206. Sugita, M., et al. 1975. Biochim. Biophys. Acta 398, 125. |