Form: 50 Tests

Detection Method: Flow cytometry or fluorescence microscopy

Assay Time: 4 h

Sample Type: Cells

Kit Contents: Wash Concentrate, Binding Protein-FITC Conjugate, and a user protocol.

Comments: Assay kit used to detect oxidative damage to DNA in vitro. Based on the direct binding of a fluorescent probe to the DNA adduct 8-oxoguanine, a major oxidation product and an important indicator of free radical-induced DNA damage and oxidative stress. The FITC-conjugate binds to 8-oxoguanine in damaged cells and fluorescence is monitored using flow cytometery (excitation 495 nm, emission 515 nm).

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