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VEGF Signaling Pathway

Inhibitor Libraries
  p38 MAP Kinase Inhibitor VI, JX401
Cat. No. 506157  
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Mitogen Activated Protein Kinase (MAPK)

N-(2-Methoxy-4-thiomethyl)benzoyl-4-benzylpiperidine

Off-white solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable piperidinamide compound that acts as a reversible and highly potent inhibitor of MAPK p38a (IC50 = 32 nM) with no detectable activity against p38g even at concentrations as high as 10 µM. Shown to effectively block the differentiation of L8 myoblasts to myotubes at 10 µM in a reversible manner. Not a competitive inhibitor with respect to either ATP or substrate. Purity: ≥98% by HPLC. CAS 349087-34-9.

Ref.: Friedmann, Y., et al. 2006. Mol. Pharmacol. 70, 1395.
R: 36/37/38; S: 22-24/25-36/37/39

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5 mgY€109


SolubilityMolecular FormulaMol. Wt.
DMSO or EtOH C21H25NO2355.5 


Material Safety Data Sheets:
506157: p38 MAP Kinase Inhibitor VI, JX401 - English
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Related Categories:
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Mitogen Activated Protein Kinase (MAPK)