Palmitoyl Trifluoromethyl Ketone White solid. A novel Ca2+-independent and reversible inhibitor of phospholipase A2 (PLA2; IC50 = 3.8 µM). May also inhibit Ca2+-dependent PLA2 at much higher concentrations (IC50 = 45 µM). Purity: ≥97% by TLC. Ref.: Conde-Frieboes, K., et al. 1996. J. Am. Chem. Soc. 118, 5519. Lio, Y.C., et al. 1996. Biochim. Biophys. Acta 1302, 55. Ackermann, E.J., et al. 1995. J. Biol. Chem. 270, 445. |
