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SID: 26759317

Inhibitor Libraries

Inhibitor Database

Inhibitor Resource
  Parthenolide, Tanacetum parthenium
Cat. No. 512732  
All Categories » Calbiochem » Inhibitors » Lipid Signaling » Cyclooxygenase (COX)

White solid. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. A cell-permeable sesquiterpene lactone with anti-inflammatory, antisecretory, and spasmolytic properties. Inhibits the expression of COX-2 and proinflammatory cytokines (TNF-a and IL-1) in LPS-stimulated macrophages. Also inhibits NF-kB and activation of MAP kinase. Purity: ≥97% by TLC. RTECS LY4220000, CAS 20554-84-1.

Ref.: Wong, H.R., et al. 1999. Biochem. Biophys. Res. Comm.262, 375. Bork, P.M., et al. 1997. FEBS Lett. 402, 85. Hwang, D., et al. 1996. Biochem. Biophys. Res. Commun. 226, 810. Barsby, R.W., et al. 1992. J. Pharm. Pharmacol. 44, 737. Sumner, H., et al. 1992. Biochem. Pharmacol. 43, 2313.
R: 20/21/22-40-42/43; S: 22-36

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50 mgY$68.00


SolubilityMolecular FormulaMol. Wt.
DMSO or EtOH C15H20O3 248.3 


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Material Safety Data Sheets:
512732: Parthenolide, Tanacetum parthenium - English
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Related Categories:
All Categories » Calbiochem » Inhibitors » Lipid Signaling » Cyclooxygenase (COX)