2-Amino-1,9-dihydro-9-[4-hydroxy-3-(hydroxymethyl)butyl]-6H-purin-6-one White solid. PACKAGED UNDER INERT GAS. A carba analog of Ganciclovir (Cat. No. 345700). Active against several herpes viruses (IC50 = 37.9 µM for HHV-6A and 77.8 µM for HHV-6B). Induces apoptosis effectively without exerting much genotoxicity. Purity: ≥98% by HPLC. CAS 39809-25-1. Merck Index: 15, 7083
Ref.: Leary, J.J., et al. 2002.Antimicrob. Agents Chemother. 46, 762. Amjad, M., et al. 2001. Microbiol. Immunol. 45, 233. Thust, R., et al. 2000. Cancer Gene Ther. 7, 107. Thust, R., et al. 1996. Antiviral Res. 31, 105. Shaw, T., et al. 1994. Antimicrob. Agents Chemother. 38, 719. Harnden, M.R. 1989. J. Med. Chem. 32, 1738.
R: 46-60-61; S: 36/37/39-45-53 |
