Pre-B Cell Stimulation Factor/Stromal Cell-Derived Factor-brhPDGF-AA Lyophilized. Lyophilized from a sterile-filtered solution in 30% acetonitrile, 0.1% TFA. Recombinant, human platelet derived growth factor AA (disulfide-linked dimer of two A-chain monomers) expressed in E. coli. Amino acid sequence is the long form of mature human PDGF-A chain and is identical to that of the native human nucleotide sequence except for the addition of an N-terminal methionine group. Implicated in the differentiation of cells of the oligodendrocyte lineage. Biological activity: 1-3 ng/ml. Purity: ≥97% by SDS-PAGE. Contaminants: Endotoxin: ≤1 EU/µg PDGF-AA. Merck Index: 14, 7525 Ref.: Butt, A.M., et al. 1997. J. Neurosci. Res. 48, 588. Westermark, B., and Heldin, C.-H. 1991. Cancer Res. 51, 5087. Betsholtz, C., et al. 1986. Nature 320, 695. Raines, E.W., et al. 1985. Methods Enzymol. 109, 749. |