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  Pravastatin, Sodium Salt
Cat. No. 524403  
All Categories » Calbiochem » Inhibitors » Lipid Signaling » 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Reductase

(bR,dR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-b,d,6-trihydroxy-2-methyl-8[(2S)-2-methyl-1-oxobutoxyl]-1-naphthaleneheptanoic Acid Na
3b-Hydroxycompactin, Na

White crystalline solid. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A water-soluble, competitive 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that potently blocks in vivo cholesterol synthesis (Ki ~1 nM). Offers cardioprotection. Also acts as an immunomodulator and an inhibitor of ras p21 isoprenylation. Purity: ≥98% by HPLC. RTECS QJ7185000, CAS 81131-70-6.

Merck Index: 14, 7714
Ref.: Kwak, B., et al. 2000. Natl. Med. 6, 1399. Hamelin, B.A., and Turgeon, J., 1998. Trends Pharmacol. Sci. 19, 26. Narisawa, T., et al. 1996. Jpn. J. Cancer Res. 87, 798. Cohen, L.H., et al. 1993. Biochem. Pharmacol. 45, 2203. Koga, T., et al. 1990. Biochim. Biophys. Acta. 1045, 115. Yoshino, G., et al. 1986. Diabetes Res. Clin. Pract. 2, 179

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25 mgY€96*

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524403
Hazardous MaterialsAttention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.

SolubilityMolecular FormulaMol. Wt.
H2C23H35O7.Na 446.5 


Related Literature:

Diabetes and Obesity Brochure

Biologics 32.4

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524403: Pravastatin, Sodium Salt - English
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Related Categories:
All Categories » Calbiochem » Inhibitors » Lipid Signaling » 3-Hydroxy-3-Methylglutaryl Coenzyme A (HMG-CoA) Reductase