PI-3,4-P2, 5NH4 White solid. HYGROSCOPIC. PACKAGED UNDER INERT GAS. Activates Ca2+-insensitive PKC isotypes d, e, and h. Also activates Akt, a serine/threonine kinase (also known as PKBa or Raca) by directly interacting with the Akt plekstrin homology (PH) domain. Purity: ≥98% by NMR. Ref.: Franke, T.F., et al. 1997. Science 275, 665. Ireton, K., et al. 1996. Science 274, 80. Toker, A., et al. 1994. J. Biol. Chem. 269, 32358. R: 36/37/38; S: 26-36 |