cGMP-inhibited phosphodiesterase 3B PDE3B Liquid. In 150 mM NaCl, 10 mM Tris, pH 8.3. Full-length, recombinant, human phosphodiesterase 3B expressed in S. frugiperda insect cells using a baculovirus expression system. An important component of insulin and cAMP-dependent signaling. Supplied as a partially purified preparation. Activity: ≥0.5 units/µl. One unit is defined as the amount of enzyme that will convert 1 pmole cAMP to AMP per min at pH 7.5, 30°C. Ref.: Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39. Kitamura, T., et al. 1999. Mol. Cell. Biol. 19, 6286. Degerman, E., et al. 1997. J. Biol. Chem. 272, 6823. |