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  Phosphodiesterase 4C2, Human, Recombinant, S. frugiperda
Cat. No. 524737  
All Categories » Calbiochem » Proteins and Enzymes » Phosphodiesterases

cAMP-Specific Phosphodiesterase 4C2
PDE4C2

Liquid. In 150 mM NaCl, 10 mM Tris-HCl, pH 8.3. AVOID FREEZE/THAW CYCLES. Full-length, recombinant, human phosphodiesterdase 4C2 expressed in S. frugiperda insect cells using a baculovirus expression system. Supplied as a partially purified preparation of the catalytically active enzyme. Activity: ≥ 0.5 units/µl. One unit is defined as the amount of enzyme that will convert 1 pmol cAMP to AMP per min at 30°C, pH 7.5.

Ref.: Gibson, L.C.D., et al. 2006. Eur. J. Pharmacol. 538, 39. Sullivan, M., et al. 1999. Cell Signal. 11, 735. Engels, P., et al. 1995. FEBS Lett. 358, 305.

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Phosphodiesterase 4C2 was treated with increasing concentration of the inhibitor, rolipram, and the activity assayed. the IC50 for this inhibition is 7.87 µM.

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All Categories » Calbiochem » Proteins and Enzymes » Phosphodiesterases