N-(a-Rhamnopyranosyloxyhydroxyphosphinyl)-L-leucyl-L-tryptophan, 2Na White lyophilized solid. PROTECT FROM LIGHT. HYGROSCOPIC. Inhibits some metalloendopeptidases. Highly specific inhibitor of thermolysin. Inhibits the conversion of big endothelin-1 to endothelin (IC50 = 4.6 µM). Purity: Single spot by TLC. Effective concentration: 1-10 µM. Ref.: Balwierczxak, J.L., et al. 1995. Biochem. Pharmacol. 49, 291. Howell, S., et al. 1993. Biochem. J. 290, 159. |