Return to our Home Page


Tech Resources
Data Sheet
MSDS - English
Other Languages
Selected Citations
Certificate of Analysis
Store
-20°C-20°C
Ship
Shipped with Blue Ice
<br>
Shipped with blue ice (water ice)!Blue ice
IrritantIrritant
Note: Store and Ship conditions may differ.
See Key
PubChem
SID: 26759389

Inhibitor Resource

Inhibitor Libraries

Kinase Kit Resource
  InSolution™ PP2
Cat. No. 529576  
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Protein Tyrosine Kinase (PTK) » Non-Receptor

Clear and colorless liquid. A 10 mM (1 mg/331 µl) solution of PP2 (Cat. No. 529573) in DMSO. PROTECT FROM LIGHT. PACKAGED UNDER INERT GAS. Purity: ≥95% by HPLC.

Ref.: Hanke, J.H., et al. 1996. J. Biol. Chem. 271, 695.
R: 36/37/38; S: 23-26-36

Need additional information about this product? Email our Technical Service department at: technical@calbiochem.com

 Related information for this product is available:

EMD Chemicals Inc. USD list price is displayed (pricing with local distributors may vary). NOTE: In Stock status is based on item availability worldwide.

Size
In Stock
Qty
Select Country Above
For Pricing Information
1 mgY$105.00


SolubilityMolecular FormulaMol. Wt.
 C15H16ClN5 301.8 


Related Literature:

Protein Kinase and Related Tools Brochure

Material Safety Data Sheets:
529576: InSolution™ PP2 - English
Bulgarian
Danish
Dutch
Finnish
French
German
Greek
Hungarian
Italian
Korean
Norwegian
Polish
Portuguese
Spanish
Swedish

Related Categories:
All Categories » Calbiochem » Inhibitors » Kinase and Phosphatase » Protein Tyrosine Kinase (PTK) » Non-Receptor

Selected Citations:
  1. Elke Heiss, et al. (2006) Identification of Y589 and Y599 in the juxtamembrane domain of Flt3 as ligand-induced autophosphorylation sites involved in binding of Src family kinases and the protein tyrosine phosphatase SHP2. Blood in press,.
  2. Farahdiba Jafri, et al. (2006) Constitutive ERK1/2 activation by a chimeric neurokinin NK1 receptor-beta-arrestin1 fusion protein: Probing the composition and function of the G protein-coupled receptor 'signalsome'. Journal of Biological Chemistry in press,.
  3. Ana Olivera, et al. (2006) IgE-dependent activation of sphingosine kinase 1 and 2 and secretion of sphingosine-1-phosphate requires Fyn kinase and contributes to mast cell responses. Journal of Biological Chemistry 281, 2515-2525.
  4. Ellen J. Tisdale and Cristina R. Artalejo. (2006) Src-dependent aPKC/ tyrosine phosphorylation is required for aPKC/ association with Rab2 and glyceraldehyde-3-phosphate dehydrogenase on Pre-golgi intermediates. Journal of Biological Chemistry 281, 8436-8442.
  5. Malcolm A. Meyn, et al. (2005) Src family kinase activity is required for murine embryonic stem cell growth and differentiation. Molecular Pharmacology 68, 1320-1330.
  6. Justin M. Summy, et al. (2005) AP23846, a novel and highly potent Src family kinase inhibitor, reduces vascular endothelial growth factor and interleukin-8 expression in human solid tumor cell lines and abrogates downstream angiogenic processes. Molecular Cancer Therapeutics 4, 1900-1911.
  7. Jose G. Trevino, et al. (2005) Expression and activity of Src regulate interleukin-8 expression in pancreatic adenocarcinoma cells: implications for angiogenesis. Cancer Research 65, 7214-7222.
  8. Xinbo Liao, et al. (2003) Androgen stimulates matrix metalloproteinase-2 expression in human prostate cancer. Endocrinology 144, 1656-1663.