2,2-Bis(hydroxymethyl)-1-azabicyclo[2,2,2]octan-3-one
p53 Reactivation and Induction of Massive Apoptosis Off-white solid. HYGROSCOPIC. PACKAGED UNDER INERT GAS. A cell-permeable quinuclidinone analog with antitumor properties. Restores biochemical and biological function to mutant p53 and induces p53-dependent apoptosis in vitro and in vivo. Induces apoptosis in breast cancer cells expressing mutant p53. Purity: ≥95% by NMR. Ref.: Bykov, V.J., et al. 2002. Nat. Med. 8, 282. | 
